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Accuracy of posteroanterior cephalogram landmarks and measurements identification using a cascaded convolutional neural network algorithm: A multicenter study

Korean Journal of Orthodontics 2024³â 54±Ç 1È£ p.48 ~ 58
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ÇѼºÈÆ ( Han Sung-Hoon ) - 
ÀÓÁö¼· ( Lim Ji-Sup ) - 
±èÁؽĠ( Kim Jun-Sik ) - 
Á¶ÁøÇü ( Cho Jin-Hyoung ) - Chonnam National University School of Dentistry Department of Orthodontics
È«¹ÌÈñ ( Hong Mi-Hee ) - Kyungpook National University School of Dentistry Department of Orthodontics
±è¹ÎÁö ( Kim Min-Ji ) - 
±è¼öÁ¤ ( Kim Su-Jung ) - 
±èÀ±Áö ( Kim Yoon-Ji ) - 
±è¿µÈ£ ( Kim Young-Ho ) - 
ÀÓ¼ºÈÆ ( Lim Sung-Hoon ) - Chosun University College of Dentistry Department of Orthodontics
¼º»óÁø ( Sung Sang-Jin ) - 
°­°æÈ­ ( Kang Kyung-Hwa ) - Wonkwang University School of Dentistry Department of Orthodontics
¹é½ÂÇР( Baek Seung-Hak ) - 
ÃÖ¼º±Ç ( Choi Sung-Kwon ) - Wonkwang University School of Dentistry Department of Orthodontics
±è³²±¹ ( Kim Nam-Kug ) - 

Abstract


Objective: To quantify the effects of midline-related landmark identification on midline deviation measurements in posteroanterior (PA) cephalograms using a cascaded convolutional neural network (CNN).

Methods: A total of 2,903 PA cephalogram images obtained from 9 university hospitals were divided into training, internal validation, and test sets (n = 2,150, 376, and 377). As the gold standard, 2 orthodontic professors marked the bilateral landmarks, including the frontozygomatic suture point and latero-orbitale (LO), and the midline landmarks, including the crista galli, anterior nasal spine (ANS), upper dental midpoint (UDM), lower dental midpoint (LDM), and menton (Me). For the test, Examiner-1 and Examiner-2 (3-year and 1-year orthodontic residents) and the Cascaded-CNN models marked the landmarks. After point-to-point errors of landmark identification, the successful detection rate (SDR) and distance and direction of the midline landmark deviation from the midsagittal line (ANS-mid, UDM-mid, LDM-mid, and Me-mid) were measured, and statistical analysis was performed.

Results: The cascaded-CNN algorithm showed a clinically acceptable level of point-to-point error (1.26 mm vs. 1.57 mm in Examiner-1 and 1.75 mm in Examiner-2). The average SDR within the 2 mm range was 83.2%, with high accuracy at the LO (right, 96.9%; left, 97.1%), and UDM (96.9%). The absolute measurement errors were less than 1 mm for ANS-mid, UDM-mid, and LDM-mid compared with the gold standard.

Conclusions: The cascaded-CNN model may be considered an effective tool for the auto-identification of midline landmarks and quantification of midline deviation in PA cephalograms of adult patients, regardless of variations in the image acquisition method.

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Artificial intelligence; Convolutional neural network; Posteroanterior cephalograms

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